Saturday June 2, 2007
Linezolid infusion and exposure to light

Case: You have a patient diagnosed with vancomycin-resistant enterococci (VRE) and has been started on linezolid (Zyvox). While evaluating patient at bedside you saw a bag labelled with linezolid, due to infuse in 30 minutes. What would be your instruction to pharmacy ?

Answer: To protect the infusion bag of linezolid from light. Linezolid infusion bag need to be protected from light while awaiting infusion to avoid degradation. Once infusion is started, bag can be unwrap.Note: IV Zyvox may exhibit a yellow color that can intensify over time, but it is a benign effect and does not affect potency.


Reference: click to get abstract

1. Zyvox - rxlist.com